Affective control and life satisfaction in thalassemics

Carmela Mento, Basilia Piraino, Amelia Rizzo, Roberta Vento, Luciana Rigoli, Emanuela Moschella, Carmelo Salpietro, Salvatore Settineri


Background. Thalassemia is a chronic disease that can lead to an impact on psychological functioning and social behavior of patients. However, still little is known about the specific psychological aspects of the disease, such as the degree of tension, life satisfaction and affective control, especially in adult patients.Aim. The purpose of this study is to investigate whether patients with thalassemia have specific psychological pattern relating to the dimensions of tension, satisfaction and quality of life, management of affection.Method. We evaluated 31 patients with thalassemia major and intermedia (19 women and 12 men) aged between 18 and 50 years (M = 34 + 16), belonging to the Complex Unit of Medical Genetics. For the evaluation were used the Profile of Mood States (POMS), the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and the Rorschach test.Results. The findings show an inverse relationship between the levels of self-reported tension and the affective control indicators at Rorschach. Life satisfaction, instead, seems to vary according to the severity of the disease - major vs. intermediate - and the type of therapy.Conclusions. An understanding of the psychological mechanisms involved in thalassemia, both self-reported and projective, can contribute to a wider patient take-over, by considering the subjective aspects related to the psychological and socio-emotional well-being, fundamental in the care compliance.


thalassaemia; affective control; quality of Life

Full Text:



Anie, K. A., & Massaglia, P. (2001). Psychological therapies for thalassaemia. Cochrane Database Syst Rev 3.

Aydin, B., Yaprak, I., Akarsu, D., Ökten, N., & Ülgen, M. (1997). Psychosocial aspects and psychiatric disorders in children with thalassemia major. Pediatrics International, 39(3), 354-357.

Birgens, H., & Ljung, R. (2007). The thalassaemia syndromes. Scandinavian journal of clinical & laboratory investigation, 67(1), 11-26.

Bohm, E. (1958). A textbook in Rorschach diagnosis. New York: Grune & Stratton.

Bornstein, R. F., Bowers, K. S., & Bonner, S. (1996). Effects of induced mood states on objective and projective dependency scores. Journal of Personality Assessment, 67(2), 324-340.

Carbone, S. (2014). Thalassemia in Messina: a sociological approach to chronic disease. Thalassemia Reports, 4(1).

Daar, S., & Pathare, A. V. (2006). Combined therapy with desferrioxamine and deferiprone in beta thalassemia major patients with transfusional iron overload. Annals of hematology, 85(5), 315-319.

Dumitrascu, N. (2011). The Impact of Induced Mood on Visual Information Processing. The University Of Toledo.

Endicott, J., Nee, J., Harrison, W., & Blumenthal, R. (1993). Quality of life enjoyment and satisfaction questionnaire. Psychopharmacol Bull, 29(2), 321-326.

Galanello, R., & Origa, R. (2010). Review: Beta-thalassemia. Orphanet J Rare Dis, 5(11).


INTERNATIONAL JOURNAL OF PSYCHOLOGICAL RESEARCH Affective control and life satisfaction in Thalassemia

Mento et al. (2014) int.j.psychol.res. 8 (1) PP. 91 - 98

Goldfarb, W. (1945). The Animal Symbol in the Rorschach Test, and an Animal Association Test. Rorschach Research Exchange, 9(1), 8-22.

Guasco, G., La Mantia, A., & Cuniolo, A. (1986). [Psychological problems of thalassemic subjects]. La Pediatria medica e chirurgica: Medical and surgical pediatrics,9(3), 269-279.

Jian-zhong, Z. H. O. U. (2003). The Cultural Connotation of Orchid and its Orientation of Personality in Confucianism. Southeast Culture, 7, 009.

Maggio, A., Giambona, A., Cai, S. P., Wall, J., Kan, Y. W., & Chehab, F. F. (1993). Rapid and simultaneous typing of hemoglobin S, hemoglobin C, and seven Mediterranean beta-thalassemia mutations by covalent reverse dot-blot analysis: application to prenatal diagnosis in Sicily. Blood, 81(1), 239-242.

Marzo, R. D., Dowling, C. E., Wong, C., Maggio, A., & Kazazian, H. H. (1988). The spectrum of β‐thalassaemia mutations in Sicily. British journal of haematology, 69(3), 393-397.

McNair, D. M., Lorr, M., & Droppleman, L. F. (1971). POMS: profile of mood states. Educational and Industrial Testing Service: San Diego.

Mento C., Galletti F., Galletti B., Longo P., Bitto E., Rizzo A., & Settineri S. (2014). Representation, Projection and Cochlear Implant: a single case study. Mediterranean Journal of Clinical Psychology, vol. 2 n. 1.

Messina, G., Colombo, E., Cassinerio, E., Cesaretti, C., Marcon, A., Zanaboni, L., Baldini M., Cappellini, M. D. (2010). Pregnant women affected by thalassemia major: a controlled study of traits and personality. Journal of research in medical sciences 15 (2), 100-106.

Messina, G., Colombo, E., Cassinerio, E., Ferri, F., Curti, R., Altamura, C., & Cappellini, M. D. (2008). Psychosocial aspects and psychiatric disorders in young adult with thalassemia major. Internal and emergency medicine, 3(4), 339-343.

Pakbaz Z, Treadwell M, Yamashita R, Quirolo K, Foote D, Quill L, Singer T, Vichinsky EP (2005) Quality of Life in Patients with Thalassaemia Intermedia Compared to Thalassaemia Major. New York Academy of Sciences 1054 (1) 457-461.

Palma, A., Vullo, C., Zani, B., & Facchini, A. (1998). Psychosocial integration of adolescents and young adults with thalassemia major. Annals of the New York Academy of Sciences, 850(1), 355-360.

Passi Tognazzo, D. (1994). Il Metodo Rorschach, Manuale di psicodiagnostica su modelli di matrice europea. Firenze: Giunti Editore.

Powell, W. N., Rodarte, J. G., & Neel, J. V. (1950). The occurrence in a family of Sicilian ancestry of the traits for both sickling and thalassemia. Blood,5(10), 887-897.

Rorschach, H. (1927). Rorschach Test – Psychodiagnostic Plates. Cambridge, MA: Hogrefe Publishing

Rose, T., Kaser-Boyd, N., & Maloney, M. P. (2001). Essentials of Rorschach Assessment. Essentials of Psychological Assessment Series. John Wiley & Sons, Inc., 605 Third Avenue, New York, NY 10158.

Sandler, J. (Ed.). (2012). Projection, identification, projective identification. Karnac Books.

Sandler, J., & Ackner, B. (1951). Rorschach content analysis: an experimental investigation. British Journal of Medical Psychology,24(3), 180-201.

Settineri S., Lo Presti E., Liotta M. and Mento C. (2013). Trauma and the Father Image: Fantasies and Complexes in the Rorschach Test. The Open Psychology Journal vol. 6 p. 1-5.

Shaligram, D., Girimaji, S. C., & Chaturvedi, S. K. (2007). Psychological problems and quality of life in children with thalassemia. The Indian Journal of Pediatrics, 74(8), 727-730.

Telfer, P., Constantinidou, G., Andreou, P., Christou, S., Modell, B., & Angastiniotis, M. (2005). Quality of life in thalassemia. Annals of the New York Academy of Sciences, 1054(1), 273-282.

Tsiantis, J., Dragonas, T. H., Richardson, C., Anastasopoulos, D., Masera, G., & Spinetta, J. (1996). Psychosocial problems and adjustment of children with β-thalassemia and their families. European child & adolescent psychiatry,5(4), 193-203.

Weatherall, D. J., & Clegg, J. B. (2008). The thalassaemia syndromes. John Wiley & Sons.

Zani, B., Di Palma, A., & Vullo, C. (1995). Psychosocial aspects of chronic illness in adolescents with thalassaemia major. Journal of adolescence, 18(4), 387-402.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.