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Cuartas Arias, J. M., & López Jaramillo, C. A. (2013). Probables interacciones entre el receptor de oxitocina (OXTR) y genes candidatos asociados a la psicopatía. International Journal of Psychological Research, 6, 109–116. https://doi.org/10.21500/20112084.725
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Resumen

La psicopatía es el resultado de una compleja interacción de factores biológicos y ambientales, ambos participan en la expresión final del fenotipo y pueden modular la variación en inicio, deterioro y severidad; sin embargo, hasta ahora no se han logrado determinar vías moleculares circunscritas y su interacción con los factores ambientales que modelen su expresión. No obstante, más allá de los avances en la evaluación diagnóstica, hay dificultades en la construcción de un modelo neurobiológico que contribuya a discriminar la conducta antisocial. Por lo tanto, explorar los mecanismos genético-moleculares, bioquímicos y hormonales implicados en las diferentes vías neurofisiológicas moduladas por genes candidatos, podría contribuir significativamente en determinar cómo los hallazgos neurobiológicos impactan las diferencias individuales en la expresión de la psicopatía. Este artículo tiene el propósito de profundizar en aquellos mecanismos neurobiológicos que subyacen a la psicopatía a partir de la expresión y regulación del sistema oxitocinérgico.

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Referencias

Arias, M. C. (2011). Functional enviromics and personality disorders. International Journal of Psychological Research, 4(2), 5-8.
Aron, A., Ketay, S., Hedden, T., Aron, E. N., Rose Markus, H., & Gabrieli, J. D. (2010). Temperament trait of sensory processing sensitivity moderates cultural differences in neural response. [Research Support, N.I.H., Extramural]. Social cognitive and affective neuroscience, 5(2-3), 219-226. doi: 10.1093/scan/nsq028
Bakermans-Kranenburg, M. J., & van Ijzendoorn, M. H. (2013). A sociability gene? Meta-analysis of oxytocin receptor genotype effects in humans. Psychiatric genetics. doi: 10.1097/YPG.0b013e3283643684
Belsky, J. (1997). Variation in susceptibility to rearing influences: an evolutionary argument. PsycholInquiry, 8, 182-186.
Cacioppo, J. T., Cacioppo, S., & Boomsma, D. I. (2013). Evolutionary mechanisms for loneliness. Cognition & emotion. doi: 10.1080/02699931.2013.837379
Caldwell, J. D., Brooks, P. J., Jirikowski, G. F., Barakat, A. S., Lund, P. K., & Pedersen, C. A. (1989). Estrogen alters oxytocin mRNA levels in the preoptic area. Journal of neuroendocrinology, 1(4), 273-278. doi: 10.1111/j.1365-2826.1989.tb00115.x
Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., . . . Poulton, R. (2002). Role of genotype in the cycle of violence in maltreated children. [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]. Science, 297(5582), 851-854. doi: 10.1126/science.1072290
Clonniger, C., Rakic, S. y Pezybeckt, D. (1993). A psychobiological model of temperament and character. Archives of General Psychiatric., 50(975-990).
Cordell, H. J., & Clayton, D. G. (2005). Genetic association studies. Lancet, 366(9491), 1121-1131. doi: S0140-6736(05)67424-7 [pii]10.1016/S0140-6736(05)67424-7
Cuartas Arias, J. M., Palacio Acosta, C. A., Valencia, J. G., Montoya, G. J., Arango Viana, J. C., Nieto, O. C., . . . Ruiz-Linares, A. (2011). Exploring epistasis in candidate genes for antisocial personality disorder. [Research Support, Non-U.S. Gov't]. Psychiatric genetics, 21(3), 115-124. doi: 10.1097/YPG.0b013e3283437175

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